Scientist Method Development Chromatography
AnaBioTec provides analytical services for characterization, assay development and quality assessment of novel and established medicines, ranging from synthetic molecules and biologics, to cell & gene therapies. With more than 25 years of experience we contribute to these medicines of tomorrow by helping our customers to accelerate their drug development journey. We support startups, biotech as well as large pharma companies worldwide from pre-clinical drug development, through clinical phases I, II, III all the way to commercialised treatments. We take proud in our flexibility, diligence and science thereby operating as an extension of our clients with tailored solutions and pro-active, science driven advice. To achieve all this, AnaBioTec is set-up as a workspace with open doors where all our employees are encouraged to continuously improve & grow and are welcomed to actively contribute to the goals of AnaBioTec.
Function
As a Scientist at Anabiotec, you will act as a scientific lead in the analytical lifecycle of (bio)-pharmaceutical products. Your mission is to bridge the gap between complex client needs and robust laboratory solutions.
- Design, optimize, and troubleshoot complex chromatographic methods (primarily HPLC/UPLC) for a diverse portfolio, including small molecules, peptides, oligonucleotides, and proteins/antibodies.
- You will act as the Subject Matter Expert (SME) for Liquid Chromatography guiding the lab team through technical hurdles.
- Interact with international biopharma clients to define analytical strategies, discuss scientific data, and provide expert advice on regulatory requirements.
- You lead the transition of methods from development to qualification and validation, ensuring they are "fit-for-purpose" according to ICH guidelines.
- Uphold the highest standards of data integrity. Ensure all work is documented and reported according to Good Documentation Practices (GDocP) and within the framework of GLP/GMP environments where required.
- Innovation & Efficiency: Implement Design of Experiments (DoE) and Quality by Design (QbD) principles to streamline development and ensure method robustness.
Profile
We are looking for a scientist who combines deep technical hands-on expertise with the strategic mindset required to thrive in a fast-paced CRO.
- PhD in Chemistry, Pharmacy, Biochemistry, or a related scientific field. Candidates with a Master's degree and extensive, high-level industry experience in method development are also encouraged to apply.
- Technical Expertise
- Expert-level knowledge of LC (HPLC/UPLC) and Mass Spectrometry (LC-MS/MS).
- Proven experience working with "New Modalities": Oligonucleotides (IP-RP, AEX), Peptides, and Large Molecules (mAbs, proteins) is a plus.
- Experience with Empower and Chromeleon.
- Familiarity with other separation techniques like Gas Chromatography (GC) and Capillary Electrophoresis (CE) is an advantage.
- Understanding of ICH Q14 principles and method validation according to ICH Q2 within GxP environments and a commitment to meticulous documentation.
- Knowledge of statistical tools and Design of Experiments (DoE) is a plus.
- You have the ability to look beyond the immediate test and understand the client's broader drug development goals.
- Comfortable managing multiple projects simultaneously in a dynamic, deadline-driven laboratory environment.
- Excellent command of English (written and spoken). Ability to translate complex data into clear reports and presentations for clients. Knowledge of Dutch is an asset.
Offer
- You will be part of the anacura group, a family owned, long term focused and ambitious laboratory organization.
- You will join a dynamic team and have a position with autonomy and responsibility with opportunities to take initiatives to support further growth.
- You will be offered a competitive salary with fringe benefits, a green work environment and the possibility to join our bike lease program, flexible working hours, a healthy lunch, and a pleasant fun club.
- You are stimulated in your personal growth; we build on your talents in accordance with our ambitions.
Interested?
Your application will be considered quickly and with the greatest confidentiality. For additional information please contact Britt Van de Velde: jobs@anacura.com or +32 9 257 15 42.
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